Research


Adaptive Optic Microscope

Project

Project Overview

Current biological imaging suffers from image degradation s the imaging depth increases. This is due to the varying index of refraction in the optical path.

Project

Adaptive Optics (AO) technology has the potential for improving biological imaging by: Measuring the optical aberrations using wavefront sensing technology, Correcting the measured aberrations using a MEMS deformable mirror

AO requires the use of reference sources to accurately measure the wavefront distortions introduced by changes in the index of refraction in the drosophila embryo. Our research has shown that fluorescent microspheres are good candidates for use as reference sources.

Project
Fluorescent microspheres.

Project Goals

Measure the optical properties of fluorescent microsphers for use as reference sources to measure the aberrations introduced by the embryo. Find a suitable method of injecting the microspheres into the embryo at different depths.Measure the aberrations caused by the embryo. Design an AO system to compensate for the aberrations.